Two sample MR report
SLC26A2_T Proliferating against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0672558 | 0.2750887 | 0.8473489 |
| Weighted median | 3 | -0.0427996 | 0.0165263 | 0.0096035 |
| Inverse variance weighted | 3 | -0.0398683 | 0.0135715 | 0.0033071 |
| Simple mode | 3 | -0.0436824 | 0.0190004 | 0.1482473 |
| Weighted mode | 3 | -0.0435934 | 0.0199715 | 0.1607498 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0221477 | 1 | 0.8816947 |
| Inverse variance weighted | 0.1741630 | 2 | 0.9166024 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0899162 | 0.2306187 | 0.7633291 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.88e-05 | 0 | TRUE | 0.6128238 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
